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Conversely, discontinuation rates were increased to 28.1% (95% CI 27.7, 28.4) at 1 year and 43.6% (95% CI 43.2, 44.0) at 3 years when using a grace period of 60 days (ESM Table 4)

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Biernacki is a member of the APMA and ACFAS, and his patient education content on MichiganFootDoctors.com and YouTube has made him one of the most-followed foot & ankle educators on YouTube.

Investigations that may be appropriate for persistent fatigue include: Full blood count (to exclude anaemia) Thyroid function tests (TSH, free T4) Vitamin B12 and folate levels Vitamin D status Renal and liver function tests Fasting glucose and HbA1c (particularly in patients with diabetes) Patients should not discontinue Wegovy without medical guidance unless experiencing severe adverse effects